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Stocks
United Therapeutics Corporation
EL7 Factor Analysis
How we score this
Overall95
Excellent — top fifth of the marketSuper StockF 7/9SafeBetter than 95% of Market stocks, per EL7's model
FactorScoreDistributionValueAvgRank
▸
Valuation
50
17.8x17.8xAround median
▸
Growth
58
2.5%▼7.1%Around median
▸
Quality
88
17.7%▲4.5%Top tier
▸
Safety
95
—2.6xTop tier
▸
Capital Return
94
—2.12%Top tier
▸
Momentum
62
72.4%▲2.9%Around median
▸
Sentiment
42
12▲3Around median
UTHR

UTHR United Therapeutics Corporation

United Therapeutics Corporation · NASDAQ
Market Closed
497.11
▼ ⁦-1.34%⁩ (-6.75)
Market Cap$21.1B
Beta0.56
52w Low52w High
375.61609.35
Last Week
⁦+1.40%⁩
Last Month
⁦-3.57%⁩
Last 3 Months
⁦-7.95%⁩
Last Year
⁦+63.12%⁩
Fair Value
Current price$497
Analyst target · 5 analysts
$663
⁦+33%⁩
See it clearly undervalued
Range ⁦$515–$735⁩
vs
DCF (estimate)
$519
⁦+4%⁩
Sees it fairly priced
⁦7.9⁩% discount · ⁦2⁩% growth
Bottom lineThe two methods disagree — estimate range ⁦$519–$663⁩.

Estimates — analyst targets and a simplified DCF, not investment advice.

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Analyst Consensus

This section combines price targets, revision history, analyst coverage changes, and an AI summary of what changed on the Street.

Price Target· 5 analysts setting price target
$643.75
⁦+29.5%⁩
Current Price $497.11·Median $662.50
Low
$515.00
High
$735.00
Current price
$497.11
Average target
$643.75
Street summary

Analyst Forecast Analysis for United Therapeutics (UTHR)

United Therapeutics stock shows complete stability in the average price target at $636.83 over the past thirty days, with the number of analysts covering the stock holding steady at 5 analysts. The convergence between the average (636.83) and the median (635) indicates a balance in fair value estimates, despite a price gap between the low (516) and the high (735), reflecting a variance in the assessment of future growth prospects.

As of 2026-05-22
Revisions momentum · 30d
⁦+1.4%⁩
Average rating
★ 4.00
Buy
Analyst coverage
14
Buy conviction
79%
High
Target dispersion
44%
Wide
Analyst ratings over time14 analysts rating
3
8
3
Strong BuyBuyHoldSellStrong Sell
Rating trend — last 12 months3.94 → 4.00
Recent analyst moves
  • = Reiterate2026-05-21
    TD Cowen
    Buy
  • = Reiterate2026-05-07
    Bernstein
    Market Perform
  • ⬇ Downgrade2026-05-07
    William Blair
    Market Perform
Premium content
Key Financials

Ten ratios that matter, each compared against its sector median and average — so you can see whether a number is rich or cheap relative to peers in the same sector.

StockSector medianSector averagetypical sector range
MetricValuePosition within sectorVerdict
  • P/E (TTM)
    17.81x
    3.94x44.30x
    Cheap
  • Forward P/E
    16.39x
    4.64x37.16x
    Cheap
  • EV / EBITDA
    13.10x
    3.77x30.13x
    Cheap
  • FCF Yield
    5.1%
    -138.2%7.8%
    Strong
  • Revenue Growth YoY
    2.5%
    -56.9%93.8%
    Near median
  • EPS Growth YoY
    8.8%
    -160.1%130.2%
    Above average
  • Gross Margin
    86.1%
    12.8%90.7%
    Strong
  • ROIC
    17.7%
    -155.3%16.0%
    Exceptional
  • Net Debt / EBITDA
    —
    —
  • Dividend Yield
    —
    —
  • Payout Ratio
    —
    —
  • Altman Z-Score
    18.94
    -38.7417.53
    Exceptional
Financial Analysis
|

Stock Analysis

AI-generated
Based on 2026-08-07 data

Company Overview

United Therapeutics Corporation is a specialty pharmaceutical company whose commercial and development portfolio focuses on pulmonary and cardiopulmonary diseases, particularly pulmonary arterial hypertension and pulmonary hypertension associated with interstitial lung disease. Revenue depends heavily on the Tyvaso franchise in its inhaled forms, while the company is working to expand its growth sources through ralinepag for pulmonary arterial hypertension, nebulized Tyvaso for idiopathic pulmonary fibrosis, and the treprostinil SMI device. It is also developing xenotransplantation programs including UKidney, UThymoKidney, and UHeart, and added a thymus-based regenerative medicine platform through the acquisition of Thymmune Therapeutics.

In Q2 FY2026, revenue reached $783.3 million, compared with $781.5 million in Q1 FY2026, representing limited sequential growth of approximately 0.2%. Gross profit was $683.8 million, with a gross margin of approximately 87.3%, and net income rose to $333.0 million from $274.9 million, while earnings per share increased to $7.27 from $5.82. Earnings per share exceeded market expectations, but revenue fell short of expectations, explaining the mixed nature of the results.

The Tyvaso franchise generated revenue of $453 million in Q2 FY2026, or approximately 57.8% of the company’s total revenue, making it the most important commercial driver in the reported mix. Nebulized Tyvaso faced competitive pressure, while Tyvaso DPI recorded all-time highs in treatment starts, referrals, total patients, and commercial patients exiting the quarter. On a trailing twelve-month basis, revenue was $3.2 billion, gross profit was $2.7 billion, and net income was $1.3 billion.

What's Driving the Stock

  • In late June 2026, the company submitted a supplemental application to FDA for nebulized Tyvaso in idiopathic pulmonary fibrosis following the TETON-1 and TETON-2 results, targeting potential approval during 2027. If the application is granted priority review, the review period would be six months, compared with ten months under the standard pathway, making FDA’s decision on the review pathway an important factor in the launch timeline.
  • United Therapeutics also submitted a new drug application for ralinepag in pulmonary arterial hypertension following the ADVANCE OUTCOMES results, and management describes it as a multibillion-dollar opportunity due to its once-daily oral administration and the clinical benefit demonstrated by the study. The company expects potential approval during 2027, with plans to submit an investigational new drug application for ralinepag DPI during 2026.
  • Tyvaso revenue reached approximately $453 million in Q2 FY2026, with Tyvaso DPI recording all-time highs in treatment starts, referrals, and patient counts at the end of the quarter. The company nearly doubled its sales force, and representatives entered the field in early July 2026 to increase physician reach and engagement frequency in the approved indications of pulmonary arterial hypertension and pulmonary hypertension associated with interstitial lung disease.
  • Management expects the second half of FY2026 to be stronger than the first half, but it did not reaffirm or update its previous revenue growth guidance. It also maintained the pathway to a $4 billion annualized revenue run rate by the end of 2027, while acknowledging that the pathway has narrowed and that achieving it may require contributions from the launches of Tyvaso in idiopathic pulmonary fibrosis and ralinepag.
  • Patient enrollment in the TETON-PPF study is nearing completion, and the company is targeting a Phase 3 readout in the second half of 2027. Management believes the program’s success could open an opportunity at least twice the size of the idiopathic pulmonary fibrosis opportunity, but this potential remains dependent on the study results.
  • The xenotransplantation platform is advancing through three authorized clinical programs; the company expects to complete the initial cohort of six patients in UKidney EXPAND during 2026, initiate the registration-enabling UThymoKidney EXTEND study, and work toward launching EXPRESS-UHeart following FDA approval. It also plans to complete two additional commercial-scale production facilities in Minnesota and Texas by the end of 2026.

Buying & Selling Case

▲ Buying Case4 pts

  • +The company combines high profitability with limited revenue growth; gross margin was approximately 87.3% and net margin approximately 42.5% in Q2 FY2026, with net income rising 21.1% from Q1 FY2026 despite nearly flat revenue.
  • +The applications for Tyvaso in idiopathic pulmonary fibrosis and ralinepag in pulmonary arterial hypertension provide two separate regulatory catalysts during 2027, and management describes each as a multibillion-dollar opportunity. The near doubling of the sales force also supports commercial readiness, with representatives in the field since early July 2026.
  • +Tyvaso DPI demand indicators showed greater strength than the consolidated revenue figure; it ended Q2 FY2026 with all-time highs in treatment starts, referrals, total patients, and commercial patients. If these indicators translate into prescriptions and sales, they could support management’s expectation that the second half of FY2026 will outperform the first half.
  • +Development growth opportunities do not depend on only one program; in addition to Tyvaso and ralinepag, the portfolio includes treprostinil SMI, TETON-PPF, three authorized xenotransplantation studies, and the Thymmune Therapeutics platform. This diversity gives the company several opportunities to demonstrate value during 2026 and 2027, although development stages and regulatory risks vary across programs.

Valuation

Analyst consensus rates UTHR shares a “Buy,” with an average price target of $643.75, within a wide range of $515 to $735. The average target is approximately 5.6% above the 52-week range high of $609.35, while the range low is $303.08, reflecting a very wide historical valuation range and meaningful variation among analyst estimates. The data does not include a usable price-to-earnings multiple, so the available valuation is based on the target range, the 52-week range, and the ability of the 2027 catalysts to offset slowing revenue and competition in Tyvaso.

BuyAnalyst target: $643.75(+29.5%)

Figures in the text are as of 2026-08-28; the live price is shown at the top of the page.

FAQ

What drives United Therapeutics revenue, and what is its ticker UTHR?

The Tyvaso franchise generated revenue of $453 million in Q2 FY2026, equivalent to approximately 57.8% of total revenue of $783.3 million. The franchise includes nebulized Tyvaso and Tyvaso DPI, which are used within the pulmonary and cardiopulmonary disease portfolio, with the DPI formulation recording all-time highs in treatment starts, referrals, and patient counts at the end of the quarter. The company is working to expand its revenue base through ralinepag in pulmonary arterial hypertension, nebulized Tyvaso in idiopathic pulmonary fibrosis, and treprostinil SMI.

Why were the Q2 FY2026 results described as mixed?

Revenue reached $783.3 million and fell short of market expectations, while remaining nearly flat compared with revenue of $781.5 million in Q1 FY2026. In contrast, earnings per share exceeded expectations and reached $7.27, compared with $5.82 in the previous quarter. Net income rose to $333.0 million from $274.9 million, while gross profit reached $683.8 million with a margin of approximately 87.3%.

How important is Tyvaso in idiopathic pulmonary fibrosis to UTHR?

In late June 2026, the company submitted a supplemental application to FDA for nebulized Tyvaso in idiopathic pulmonary fibrosis following the TETON-1 and TETON-2 results. Management expects potential approval during 2027 and describes the opportunity as multibillion-dollar, but clarified that the initial launch in this indication would be limited to the nebulized formulation. The review takes six months if the application is granted priority and ten months under the standard pathway, and the review pathway had not been determined as of the August 7, 2026 call.

Earnings callEDGAR filings30-day newsInsider activity

Automated analysis for informational purposes only — not investment advice.

▼ Selling Case6 pts

  • −Tyvaso represents a high commercial concentration, generating $453 million of the $783.3 million in revenue in Q2 FY2026, or approximately 57.8%. Therefore, any weakness in demand, pricing, or market share for this franchise could materially affect the company’s overall results.
  • −Management acknowledged that nebulized Tyvaso is facing competitive pressure within the inhaled prostacyclin class as patients and physicians evaluate a growing number of treatment options. It also noted that physicians’ understanding of the portfolio’s advantages takes time, while describing the JASCAYD launch as strong and citing OFEV and Esbriet among the products considered in planning the launch pathway for Tyvaso in idiopathic pulmonary fibrosis.
  • −Q2 FY2026 revenue was approximately $783.3 million, compared with $781.5 million in the previous quarter, representing sequential growth of only approximately 0.2%, and revenue also fell short of both market and company expectations. This result shows that improving patient indicators for Tyvaso DPI have not yet translated into a clear acceleration in reported revenue.
  • −Management did not reaffirm or update its previous FY2026 revenue growth guidance, stating only that the second half is expected to be stronger than the first. It also said that the pathway to a $4 billion annualized revenue run rate by the end of 2027 has narrowed and may require revenue from the launches of Tyvaso in idiopathic pulmonary fibrosis and ralinepag, increasing the target’s sensitivity to approval timing and launch speed.
  • −The 2027 catalysts depend on regulatory decisions that had not been resolved as of the August 7, 2026 call; it was not known whether the Tyvaso application would receive priority review, and FDA had not specified the requirements for expanding the use of Tyvaso DPI and SMI in idiopathic pulmonary fibrosis. Management explained that the idiopathic pulmonary fibrosis launch in 2027 would be limited to nebulized Tyvaso, while launch timing and priority designation remain factors affecting the speed of new product growth.
  • −Net insider selling during the three months ended with the latest transaction on August 27, 2026, was approximately $391.2 million, with 776 sales and no purchases recorded. This is a weak trading signal on its own because insider sales may be prearranged, and the context provides no evidence that these transactions reflect a negative assessment of the company’s outlook.
What distinguishes the ralinepag program?

United Therapeutics submitted a new drug application for ralinepag in pulmonary arterial hypertension following the ADVANCE OUTCOMES study results. Management describes it as the first once-daily oral prostacyclin and believes the clinical benefit data support a multibillion-dollar opportunity. The company is targeting potential approval during 2027 and also plans to submit an investigational new drug application for the ralinepag DPI formulation during 2026.

Can UTHR reach a $4 billion annualized revenue run rate?

Management said on the August 7, 2026 call that it still sees a pathway to reaching a $4 billion annualized revenue run rate by the end of 2027, but acknowledged that this pathway has narrowed. Reaching the target may require contributions from the launches of nebulized Tyvaso in idiopathic pulmonary fibrosis and ralinepag in pulmonary arterial hypertension during 2027. The target’s sensitivity is increased because Q2 FY2026 revenue was $783.3 million and was nearly flat sequentially, and because the company did not reaffirm or update its FY2026 revenue growth guidance.

What role do xenotransplantation programs play in the United Therapeutics story?

The company has three authorized clinical programs, including UKidney EXPAND, UThymoKidney EXTEND, and EXPRESS-UHeart. It expects to complete the initial cohort of six patients in UKidney EXPAND during 2026 and is working to initiate the registration-enabling UThymoKidney study and the UHeart study following FDA approval. It also plans to complete two additional commercial-scale production facilities in Minnesota and Texas by the end of 2026 and added a thymus-based platform through the acquisition of Thymmune Therapeutics.