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TG Therapeutics, Inc.
TGTX

TGTX TG Therapeutics, Inc.

TG Therapeutics, Inc. · NASDAQ
Market Closed
56.87
▲ ⁦+0.71%⁩ (+0.40)
Market Cap$8.7B
Beta1.67
52w Low52w High
26.7659.30
Last Week
⁦+5.53%⁩
Last Month
⁦+13.15%⁩
Last 3 Months
⁦+55.21%⁩
Last Year
⁦+93.90%⁩
EL7 Factor Analysis
How we score this
Overall86
Excellent — top fifth of the marketHigh FlyerF 4/9Better than 86% of Market stocks, per EL7's model
FactorScoreDistributionValueAvgRank
▸
Valuation
20
20.6x▼17.6xBottom tier
▸
Growth
98
76.1%▲7.1%Top tier
▸
Quality
88
50.2%▲4.5%Top tier
▸
Safety
52
2.1x▲2.6xAround median
▸
Capital Return
21
—2.15%Bottom tier
▸
Momentum
98
71.4%▲2.3%Top tier
▸
Sentiment
45
6▲3Around median
Fair Value
Low confidenceCurrent price$57
Analyst target · 2 analysts
$81
⁦+42%⁩
See it clearly undervalued
Range ⁦$78–$83⁩
vs
DCF (estimate)
N/A (negative FCF)

Estimates — analyst targets and a simplified DCF, not investment advice.

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Annual plan
$17/mo
Monthly plan
$29/mo

Analyst Consensus

This section combines price targets, revision history, analyst coverage changes, and an AI summary of what changed on the Street.

Price Target· 2 analysts setting price target
$80.50
⁦+41.6%⁩
Current Price $56.87·Median $80.50
Low
$78.00
High
$83.00
Current price
$56.87
Average target
$80.50
Street summary

Bullish revision of TG Therapeutics price targets

Bullish tilt

The price target for TGTX stock has seen a strong positive revision over the last 30 days, with the average forecast jumping from $64 to $80.5, an increase of 25.78%. This adjustment reflects notable optimism from analysts, especially with forecasts stabilizing at this high level throughout the past week, indicating growing confidence in the stock's intrinsic value compared to its current price of $49.9.

As of 2026-08-11
Revisions momentum · 30d
⁦0.0%⁩
Average rating
★ 3.75
Buy
Analyst coverage
8
Buy conviction
88%
High
Target dispersion
9%
Analyst ratings over time8 analysts rating
1
6
1
Strong BuyBuyHoldSellStrong Sell
Rating trend — last 12 months3.67 → 3.75
Recent analyst moves
  • = Reiterate2026-08-04
    H.C. Wainwright
    Buy
  • = Reiterate2026-07-27
    B. Riley
    Buy
  • = Reiterate2026-06-22
    Jefferies
    Buy
Premium content
Key Financials

Ten ratios that matter, each compared against its sector median and average — so you can see whether a number is rich or cheap relative to peers in the same sector.

StockSector medianSector averagetypical sector range
MetricValuePosition within sectorVerdict
  • P/E (TTM)
    20.57x
    3.85x44.95x
    Cheap
  • Forward P/E
    28.52x
    4.71x37.71x
    Near median
  • EV / EBITDA
    67.63x
    3.78x30.25x
    Very expensive
  • FCF Yield
    -0.0%
    -139.6%7.8%
    Strong
  • Revenue Growth YoY
    76.1%
    -57.4%93.8%
    Strong
  • EPS Growth YoY
    627.6%
    -159.3%129.8%
    Exceptional
  • Gross Margin
    82.4%
    12.8%90.7%
    Strong
  • ROIC
    50.2%
    -154.2%16.1%
    Exceptional
  • Net Debt / EBITDA
    2.05x
    0.59x5.12x
    Low debt
  • Dividend Yield
    —
    —
  • Payout Ratio
    —
    —
  • Altman Z-Score
    —
    —
Financial Analysis
|

Stock Analysis

AI-generated
Based on 2026-08-03 data

Company Overview

TG Therapeutics is a biopharmaceutical company commercially focused on BRIUMVI for the treatment of relapsing multiple sclerosis, generating most of its revenue from product sales within the United States, alongside sales to its partner outside the United States and license and royalty revenue. In fiscal Q2 2026, net U.S. BRIUMVI revenue was approximately $228 million, and total product revenue was $236 million, while total revenue rose to $240 million after adding $4.5 million in license, royalty, and other revenue. The company is working to expand the franchise through a simplified intravenous initiation schedule, a self-administered subcutaneous formulation, studies in myasthenia gravis and treatment-resistant schizophrenia, as well as the azer-cel program.

Fiscal Q2 2026 delivered year-over-year growth of more than 64% in net U.S. BRIUMVI revenue, with sequential growth of approximately 17%, and the company recorded a new quarterly high in new patient starts. Gross margin for the U.S. business was approximately 87%, while total gross margin was 83% due to the mix of partner sales outside the United States and other revenue. The company reported operating income of $21.7 million and net income of $7.8 million, or $0.05 per diluted share, after operating expenses of approximately $150 million included about $55 million related to manufacturing for the subcutaneous formulation and the secondary supply source.

Historical financial results reflect the company’s transition to a larger revenue and profitability scale, with fiscal year 2025 revenue of approximately $616.3 million, gross profit of $515.6 million, and net income of $447.2 million. Revenue for the trailing twelve months ended in 2026 was approximately $700.3 million, with gross profit of $581.7 million and net income of $461.9 million. However, reported net income requires careful interpretation when assessing recurring operating strength, because fiscal Q2 2026 results showed that manufacturing expenses and investment in expansion can create a significant difference between underlying profit and reported accounting profit.

What's Driving the Stock

Earnings callEDGAR filings30-day newsInsider activity

Automated analysis for informational purposes only — not investment advice.

TG Therapeutics raised its fiscal year 2026 guidance for net U.S. BRIUMVI revenue to a range of $890–905 million and expects total global revenue of approximately $950 million, after generating $423 million in net U.S. revenue and $445 million in total revenue during the first half.
  • BRIUMVI recorded a second consecutive quarterly high in new patient starts during fiscal Q2 2026, with an increase in prescribers and improved treatment persistence, while the number of patients prescribed the treatment globally exceeded 30 thousand as of August 3, 2026.
  • The phase 3 ENHANCE study showed positive results supporting initiation of BRIUMVI with a single 600-milligram infusion instead of the day 1 and day 15 schedule; if the process proceeds as the company expects, the new schedule could become available in mid-2027, reducing the burden of an additional visit to the infusion center.
  • The proprietary subcutaneous formulation of ublituximab showed positive phase 1 bioavailability data, while the phase 3 study became fully enrolled and is targeting the release of topline results near the end of 2026 or the beginning of 2027. Successful quarterly self-administered dosing would allow the company to enter the segment representing approximately 35%–40% of the dynamic anti-CD20 market, and management estimates that pricing factors could make the addressable market more than twice the current market for the intravenous product.
  • The company expanded its clinical program during fiscal Q2 2026; it initiated a phase 2 study that could potentially support registration in myasthenia gravis and began a phase 2 study in treatment-resistant schizophrenia, while azer-cel enrollment exceeded twenty patients and expanded to include relapsing multiple sclerosis, myasthenia gravis, CIDP, and NMO.
  • Fiscal Q2 2026 results pressured the stock on August 3, 2026, after earnings per share came in below analysts’ estimates despite revenue growth and raised guidance; news reports indicated a decline ranging from 5% to 11.26% following the results and earnings call.
  • Buying & Selling Case

    ▲ Buying Case4 pts

    • +BRIUMVI combines rapid commercial growth with a strong margin; its net U.S. revenue increased by more than 64% year over year to approximately $228 million in fiscal Q2 2026, with a U.S. gross margin of approximately 87% and a new quarterly high in patient starts.
    • +The increase in fiscal year 2026 guidance to $890–905 million in net U.S. BRIUMVI revenue and approximately $950 million in global revenue provides quantitative evidence of strong demand, and the company is targeting more than $250 million in quarterly net U.S. revenue in fiscal Q4 2026.
    • +The simplified intravenous schedule and subcutaneous formulation could expand the franchise from the physician-administered segment, which represents approximately 60%–65% of the market, to the entire anti-CD20 market for relapsing multiple sclerosis under the single BRIUMVI brand and the same commercial infrastructure.
    • +At the end of fiscal Q2 2026, the company held approximately $612 million in cash, cash equivalents, and investment securities, while operating income adjusted to exclude approximately $55 million in manufacturing costs was about $76 million; this gives it the capacity to fund commercial and clinical expansion without the underlying results being loss-making in that quarter.

    ▼ Selling Case6 pts

    • −The commercial story depends heavily on BRIUMVI; of the $240 million in fiscal Q2 2026 revenue, $236 million came from product revenue, including approximately $228 million within the United States, while license, royalty, and other revenue did not exceed $4.5 million. Therefore, any slowdown in BRIUMVI adoption or problems with access and pricing could have a disproportionate effect on the company’s results.
    • −BRIUMVI operates in a competitive anti-CD20 market that includes OCREVUS, its new formulation from Roche, and self-administered treatments such as KESIMPTA; the company does not currently participate in the self-administered segment, which represents approximately 35%–40% of the dynamic market. Closing this gap depends on the success of the phase 3 study of the subcutaneous formulation and then completing the requirements needed to make it available.
    • −Earnings per share in fiscal Q2 2026 came in below analysts’ estimates, and the company recorded net income of only $7.8 million despite revenue of $240 million. Operating expenses were also approximately $150 million, including about $55 million in manufacturing costs, and the company expects $350–400 million in operating expenses during fiscal year 2026 in addition to approximately $100 million in manufacturing expenses.
    • −Management expects fiscal Q4 2026 to be the growth driver for the second half and noted seasonal factors in Q3 affecting the entire multiple sclerosis market. This means the sequential growth trajectory may not be consistent, and achieving the target of more than $250 million in quarterly net U.S. revenue depends more heavily on execution in the final quarter.
    • −The main expansion opportunities involve development and approval risks; the subcutaneous formulation remains in phase 3, the myasthenia gravis and treatment-resistant schizophrenia programs are in phase 2, while azer-cel remains in a study with more than 20 patients. Management described reports from some azer-cel participants as anecdotal and emphasized the need to generate rigorous clinical evidence before drawing conclusions.

    Valuation

    The analyst consensus is “Buy,” with an average price target of $80.5 and a narrow range between $78 and $83; the average and all targets are above the 52-week range high of $59.3. No displayed price-to-earnings ratio is available, so the stock’s valuation is based more heavily on BRIUMVI growth expectations and the results of the subcutaneous formulation, while collective optimism must be balanced against the stock’s sensitivity demonstrated on August 3, 2026, when fiscal Q2 2026 earnings per share came in below estimates.

    BuyAnalyst target: $80.5(+41.6%)

    Figures in the text are as of 2026-08-30; the live price is shown at the top of the page.

    FAQ

    What is the main revenue driver for TG Therapeutics under the ticker TGTX?

    BRIUMVI is the company’s primary commercial driver and is a treatment for relapsing multiple sclerosis. In fiscal Q2 2026, the product generated approximately $228 million in net U.S. revenue, an increase of more than 64% year over year and approximately 17% sequentially. Total product revenue, including sales to the partner outside the United States, was $236 million out of total revenue of $240 million. The number of patients prescribed BRIUMVI globally also exceeded 30 thousand as of August 3, 2026.

    What is the fiscal year 2026 revenue guidance for BRIUMVI?

    The company raised its guidance for net U.S. BRIUMVI revenue to $890–905 million in fiscal year 2026. Net U.S. revenue during the first half was approximately $423 million, while total revenue reached approximately $445 million. Management expects approximately $950 million in total global revenue in fiscal year 2026. It also aims to exit fiscal Q4 2026 with quarterly net U.S. revenue exceeding $250 million and an annualized rate exceeding $1 billion.

    How could the subcutaneous formulation expand BRIUMVI’s market?

    BRIUMVI currently participates in the physician-administered treatment segment, which represents approximately 60%–65% of the anti-CD20 market. Self-administered treatments represent approximately 35%–40% of the dynamic market, a segment in which the product does not currently participate. The subcutaneous formulation showed positive phase 1 bioavailability data, and the fully enrolled phase 3 study is evaluating a quarterly dosing regimen using an autoinjector. The company expects topline study results near the end of 2026 or the beginning of 2027 and believes pricing factors could make the addressable opportunity more than twice the current market for the intravenous product.

    Why were fiscal Q2 2026 earnings weaker than market expectations?

    In fiscal Q2 2026, TG Therapeutics recorded operating income of $21.7 million and net income of $7.8 million, or $0.05 per diluted share. Operating expenses of approximately $150 million included about $55 million related to manufacturing the subcutaneous formulation and the secondary supply source. Excluding these expenses, the company estimated operating income of approximately $76 million and net income of approximately $62 million. Nevertheless, reported earnings per share came in below analysts’ estimates on August 3, 2026, which overshadowed revenue growth and raised guidance in the market’s reaction.

    What are the most important clinical data awaited by TGTX investors?

    In fiscal Q2 2026, the company announced positive phase 3 results from the ENHANCE study, supporting initiation of BRIUMVI with a single 600-milligram infusion instead of two doses on day 1 and day 15. Phase 3 results for the subcutaneous formulation are expected near the end of 2026 or the beginning of 2027. The company also initiated a phase 2 study in myasthenia gravis and another in treatment-resistant schizophrenia. Enrollment in the azer-cel program exceeded twenty patients, with the study expanding to relapsing multiple sclerosis, myasthenia gravis, CIDP, and NMO.

    What is TG Therapeutics’ liquidity and margin position?

    The company ended fiscal Q2 2026 with approximately $612 million in cash, cash equivalents, and investment securities. Gross margin for the U.S. BRIUMVI business was approximately 87%, while total gross margin reached 83%. The company expects operating expenses between $350 and $400 million in fiscal year 2026, excluding stock-based compensation, in addition to approximately $100 million in manufacturing expenses. A significant portion of manufacturing activities could represent saleable inventory and future margin support if the related programs succeed.

  • −The average analyst price target of $80.5 is significantly above the 52-week range high of $59.3, while no displayed price-to-earnings ratio is available for the stock. This large gap makes the valuation dependent on continued BRIUMVI growth and successful franchise expansion, and the decline on August 3, 2026, following the earnings miss showed that the market quickly penalizes any gap between actual execution and elevated expectations.