EL7.AI
Strategy BuilderCOT DataAdvanced NewsResearchNewEarnings CalendarEconomic Calendar
We use cookiesPrivacy Policy
EL7.AIEL7.AI

AI Financial Intelligence
Professional analysis of central bank decisions

© 2026 EL7.AI. All rights reserved.

Markets

  • News
  • Forex
  • Stocks
  • Crypto
  • Gold
  • Commodities
  • Indices
  • ETFs

Analysis

  • Fed
  • ECB
  • BLS
  • COT
  • Economic Calendar

Learn

  • Service Guide
  • Oil

Company

  • About
  • Contact
  • Data Methodology
  • AI Disclosure
  • Pricing
  • Enterprise
  • Terms
  • Privacy
  • Security
  • WhatsApp
Status data is currently unavailable

The information provided on EL7.AI is for educational and informational purposes only and does not constitute financial advice.

Home
Stocks
Jazz Pharmaceuticals plc
EL7 Factor Analysis
How we score this
Overall94
Excellent — top fifth of the marketSuper StockF 4/9Grey zoneBetter than 94% of Market stocks, per EL7's model
FactorScoreDistributionValueAvgRank
▸
Valuation
72
16.8x▲17.8xTop tier
▸
Growth
70
12.6%▲7.1%Top tier
▸
Quality
94
10.9%▲4.5%Top tier
▸
Safety
65
2.0x▲2.6xAround median
▸
Capital Return
39
0.00%▼2.12%Bottom tier
▸
Momentum
93
109.3%▲2.9%Top tier
▸
Sentiment
45
12▲3Around median
JAZZ

JAZZ Jazz Pharmaceuticals plc

Jazz Pharmaceuticals plc · NASDAQ
Market Closed
245.80
▲ ⁦+2.21%⁩ (+5.32)
Market Cap$15.4B
Beta0.32
52w Low52w High
123.88265.05
Last Week
⁦+0.09%⁩
Last Month
⁦-4.23%⁩
Last 3 Months
⁦+3.94%⁩
Last Year
⁦+97.54%⁩
Fair Value
Current price$246
Analyst target · 14 analysts
$300
⁦+22%⁩
See it clearly undervalued
Range ⁦$229–$337⁩
vs
DCF (estimate)
$409
⁦+66%⁩
Sees it clearly undervalued
⁦7.9⁩% discount · ⁦2⁩% growth
Bottom lineThe two methods broadly agree — estimate range ⁦$300–$409⁩.

Estimates — analyst targets and a simplified DCF, not investment advice.

Compare in the screener
Premium content

Get Your Premium Account Now

  • Stock Deep Analysis
  • The Advanced News Platform
Recommended
Annual plan
$17/mo
Monthly plan
$29/mo

Analyst Consensus

This section combines price targets, revision history, analyst coverage changes, and an AI summary of what changed on the Street.

Price Target· 14 analysts setting price target
$289.50
⁦+17.8%⁩
Current Price $245.80·Median $299.50
Low
$229.00
High
$337.00
Current price
$245.80
Average target
$289.50
Street summary

Slight Rise in Consensus with a Wider Target Range

Bullish tilt

The consensus price target rose from 282.31 to 289.5 over the last 30 days, an increase of 7.19 or 2.55%. The rise was limited over the last 7 days and one day, while the number of analysts declined from 15 to 14, meaning that the improvement in consensus was not accompanied by a broader coverage base. The stock is trading at 245.8, below the consensus and median of 299.5, with a wide range between 229 and 337, reflecting notable variation in estimates.

As of 2026-09-11
Revisions momentum · 30d
⁦+2.5%⁩
Average rating
★ 4.15
Buy
Analyst coverage
⁦20 (-1)⁩
Buy conviction
90%
High
Rating activity · 30d
0↑ · 0↓
Target dispersion
44%
Wide
Analyst ratings over time20 analysts rating
7
11
1
1
Strong BuyBuyHoldSellStrong Sell
Rating trend — last 12 months4.10 → 4.15
Recent analyst moves
  • = Reiterate2026-09-11
    UBS
    Buy
  • = Reiterate2026-08-26
    Deutsche Bank
    Buy
  • = Reiterate2026-08-26
    RBC Capital
    Outperform
Premium content
Key Financials

Ten ratios that matter, each compared against its sector median and average — so you can see whether a number is rich or cheap relative to peers in the same sector.

StockSector medianSector averagetypical sector range
MetricValuePosition within sectorVerdict
  • P/E (TTM)
    16.80x
    3.94x44.30x
    Cheap
  • Forward P/E
    9.60x
    4.64x37.16x
    Very cheap
  • EV / EBITDA
    12.22x
    3.77x30.13x
    Cheap
  • FCF Yield
    10.0%
    -138.2%7.8%
    Exceptional
  • Revenue Growth YoY
    12.6%
    -56.9%93.8%
    Near median
  • EPS Growth YoY
    313.0%
    -160.1%130.2%
    Exceptional
  • Gross Margin
    84.7%
    12.8%90.7%
    Strong
  • ROIC
    10.9%
    -155.3%16.0%
    Strong
  • Net Debt / EBITDA
    1.99x
    0.60x5.10x
    Low debt
  • Dividend Yield
    0.0%
    0.0%3.9%
    Low
  • Payout Ratio
    —
    —
  • Altman Z-Score
    2.54
    -38.7417.53
    Strong
Financial Analysis
|

Stock Analysis

AI-generated
Based on 2026-08-03 data

Company Overview

Jazz Pharmaceuticals develops and markets specialized medicines for rare diseases, sleep disorders, epilepsy, and oncology. In Q2 FY2026, revenue was driven by Xywav for sleep disorders, with sales of $471 million, and Epidiolex for epilepsy, with sales of $292 million, alongside an oncology portfolio that includes Zepzelca, with sales of $106 million, Modeyso, with sales of $48 million, and Ziihera, with sales of $15 million. The company is also pursuing growth by expanding indications and dosage forms, such as Epidiolex capsules, and by developing zanidatamab, marketed as Ziihera, in additional tumor types.

Jazz reported record revenue of $1.21 billion in Q2 FY2026, up 16% year over year, including 32% growth in the oncology portfolio, 13% growth in Xywav, and 16% growth in Epidiolex. Net income according to EDGAR data was approximately $192.8 million, and earnings per share were $2.78, while adjusted non-GAAP earnings per share were $5.71, including in-process research and development expenses of $0.94 per share. Adjusted gross margin declined slightly year over year due to higher sales of Zepzelca and Modeyso, which carry third-party royalties.

The results reflect increasing diversification, but Xywav remained the largest individual product and accounted for approximately 39% of Q2 FY2026 revenue. Net income for the twelve months ended in 2026 was approximately $940.8 million on revenue of $4.6 billion, compared with a net loss of $356.1 million on revenue of $4.3 billion in FY2025. The company also generated operating cash flow of $824 million in the first half of FY2026 and repaid its convertible notes due in 2026 during the second quarter.

What's Driving the Stock

  • The company raised its FY2026 revenue guidance to a range of $4.60 billion to $4.75 billion and increased its rare sleep disorders revenue forecast to between $2.025 billion and $2.125 billion, with Xywav now expected to deliver double-digit growth instead of the previous forecast of flat to mid-single-digit growth.
  • In August 2026, Ziihera received FDA approval for the treatment of HER2-positive gastric and esophageal cancer after phase 3 data showed a 35% reduction in the risk of disease progression or death. The zanidatamab plus tislelizumab arm showed median overall survival of 26.4 months, more than seven months longer than the trastuzumab arm, while Jazz has more than 90% overlap between the targeted physicians and its existing commercial infrastructure.
  • Xywav sales rose 13% to $471 million in Q2 FY2026, with a net addition of approximately 525 patients and the number of active patients reaching approximately 17,125, up more than 12% year over year. The additions consisted of 200 patients with narcolepsy and 325 patients with idiopathic hypersomnia, while adoption of high-sodium oxybate alternatives remained limited during the first half of FY2026.
  • Epidiolex sales grew 16% to $292 million in Q2 FY2026, with 12% volume growth and no unusual U.S. inventory movements. The company submitted a new drug application to the FDA for a capsule formulation intended to facilitate use among adolescents and adults, alongside three new trials covering Lennox-Gastaut syndrome, developmental and epileptic encephalopathies, and juvenile myoclonic epilepsy.
  • Zepzelca sales reached approximately $106 million in Q2 FY2026, up 42%, and first-line maintenance use accounted for between 30% and 40% of its total U.S. sales. Modeyso also generated sales of $48 million after more than 600 patients had been treated through the end of the quarter, while Ziihera generated sales of $15 million and captured more than 50% of the addressable U.S. market for biliary tract cancer.
  • On August 12, 2026, Jazz announced the acquisition of Actio Biosciences for $820 million upfront to obtain ABS-1230 and strengthen its rare epilepsy treatment portfolio. The transaction follows the generation of $824 million in operating cash flow and the holding of $2.2 billion in cash during the first half of FY2026, but it increases the importance of disciplined execution given the reported debt burden of $4.4 billion.

Buying & Selling Case

▲ Buying Case5 pts

  • +Jazz combines 16% revenue growth in Q2 FY2026 with a shift in net results from a loss of $356.1 million in FY2025 to net income of $940.8 million for the twelve months ended in 2026, indicating tangible financial improvement supported by a multi-product commercial portfolio.
  • +Xywav has a base of approximately 17,125 patients, and its patient count grew by more than 12%, while the company believes the idiopathic hypersomnia market includes more than 37 thousand diagnosed patients seeking treatment; this leaves room for growth if it maintains its advantage as the only low-sodium oxybate and the only FDA-approved option for idiopathic hypersomnia.
  • +The FDA approval of Ziihera in August 2026 opens an additional growth opportunity, supported by a 35% reduction in the risk of disease progression or death and more than 90% overlap between targeted physicians and the existing commercial infrastructure. A permanent J-code, the JazzCares program, and Ziihera's prior presence in biliary tract cancer also provide a practical foundation for expanding use.
  • +Growth does not depend on a single asset; Epidiolex grew 16%, Zepzelca grew 42%, and the oncology portfolio grew 32% in Q2 FY2026. New Epidiolex trials and the development of zanidatamab in breast, colorectal, and lung cancers support opportunities to expand indications over several years.
  • +

Valuation

The average analyst price target is $287.86, within a wide range of $229 to $322, with a consensus Buy rating; the average is approximately 8% above the 52-week range high of $266.38, while the highest target exceeds that high by approximately 21%. This range reflects optimism about the Ziihera approval and growth in Xywav and the oncology portfolio, but the absence of a displayed price-to-earnings multiple and the wide gap between the lowest and highest targets highlight uncertainty surrounding competition in sleep disorders, erosion of Zepzelca's second-line use, and execution of the Actio Biosciences transaction.

BuyAnalyst target: $287.86(+17.1%)

Figures in the text are as of 2026-09-02; the live price is shown at the top of the page.

FAQ

What drove Jazz Pharmaceuticals' growth in Q2 FY2026?

Revenue rose 16% to a record $1.21 billion in Q2 FY2026. Xywav sales grew 13% to $471 million, and Epidiolex sales grew 16% to $292 million, while the oncology portfolio increased 32%. Within oncology, Zepzelca sales rose 42% to $106 million, and Modeyso and Ziihera recorded sales of $48 million and $15 million, respectively.

How important is the FDA approval of Ziihera to Jazz's growth?

In August 2026, the FDA approved Ziihera for the treatment of HER2-positive gastric and esophageal cancer, according to the provided news. Phase 3 data showed a 35% reduction in the risk of disease progression or death, while median overall survival with zanidatamab and tislelizumab was approximately 26.4 months, more than seven months longer than with trastuzumab. Jazz enters this expansion with more than 90% overlap among targeted physicians, a permanent J-code, and commercial infrastructure that gained experience as Ziihera reached more than 50% share of the addressable U.S. biliary tract cancer market.

Can Xywav continue growing amid competition?

Xywav added approximately 525 net patients in Q2 FY2026, including 200 with narcolepsy and 325 with idiopathic hypersomnia, bringing the total to approximately 17,125 active patients. The patient count grew by more than 12% year over year, and the company raised its outlook for the drug to double-digit growth in FY2026 after adoption of high-sodium alternatives remained limited. However, competition from generic oxybates, orexin therapies, and potential idiopathic hypersomnia products remains a risk, particularly because Xywav accounted for approximately 39% of quarterly revenue.

Earnings callEDGAR filings30-day newsInsider activity

Automated analysis for informational purposes only — not investment advice.

Operating cash flow of $824 million in the first half of FY2026 and liquidity of $2.2 billion provide capacity to fund research and development and transactions, while the convertible notes due in 2026 were repaid. The company used this flexibility to acquire Actio Biosciences for $820 million upfront and add ABS-1230 to its rare epilepsy portfolio.

▼ Selling Case7 pts

  • −Xywav still accounts for approximately 39% of Q2 FY2026 revenue, making performance sensitive to changes in competition or insurance coverage in the oxybate market. Management noted the need to monitor the availability of high-sodium alternatives and new product launches, while analysts also discussed potential competition in idiopathic hypersomnia during 2028 and the progress of orexin-2 receptor agonists.
  • −The Xywav franchise faces existing competition from high-sodium oxybate alternatives and potential competition from orexin therapies and other products for idiopathic hypersomnia. Although adoption of alternatives was limited in the first half of FY2026, the guidance increase relied partly on expectations of a more moderate impact from these alternatives in the second half, making continued weak adoption an important assumption.
  • −In Q3 FY2026, the company intends to submit a supplement to the FDA to remove Zepzelca's second-line indication following the LAGOON trial results, while its first-line maintenance indication remains unchanged. First-line maintenance accounts for only between 30% and 40% of the drug's total U.S. sales, and management expects the decline in second-line business to accelerate even though this impact is included in FY2026 guidance.
  • −Adjusted gross margin declined slightly in Q2 FY2026 due to higher sales of Zepzelca and Modeyso, which carry third-party royalties. Adjusted selling, general and administrative expenses and research and development spending each rose 11%, and the company modestly increased its selling, general and administrative expense guidance to fund commercial investment and corporate development.
  • −The acquisition of Actio Biosciences combines an upfront payment of $820 million with a reported debt burden of $4.4 billion, increasing capital allocation and execution risks if ABS-1230 does not deliver the intended clinical and commercial value. Liquidity of $2.2 billion and operating cash flow of $824 million in the first half of FY2026 mitigate this risk but do not eliminate it.
  • −Price targets reflect a high degree of optimism following the Ziihera approval and phase 3 results; the average target of $287.86 is approximately 8% above the 52-week range high of $266.38. If Xywav growth slows or Ziihera's expansion does not translate into sales as quickly as expected, this valuation could be reset despite the consensus Buy rating.
  • −Net insider selling during the three months ended with the latest transaction on August 27, 2026, was approximately $24.1 million across 11 sales and no purchases. This is a secondary trading signal rather than standalone evidence of business weakness because insider sales may be prearranged unless the data states otherwise.
What is Jazz's plan to expand Epidiolex?

Epidiolex generated sales of $292 million in Q2 FY2026, with 16% revenue growth and 12% volume growth. The company submitted a new drug application to the FDA for capsules intended to facilitate use among adolescents and adults, without changing ANDA agreements or the protection that management said extends into the late 2030s. It also initiated clinical programs covering Lennox-Gastaut syndrome in adults, developmental and epileptic encephalopathies, and juvenile myoclonic epilepsy, alongside an ongoing trial in focal seizures.

Why does Zepzelca represent both an opportunity and a risk?

Zepzelca sales grew 42% to $106 million in Q2 FY2026, driven by adoption of first-line maintenance following the IMforte trial. First-line sales accounted for between 30% and 40% of total U.S. sales, and the regimen with Tecentriq received a category 1 listing in the NCCN guidelines. Conversely, Jazz intends to submit a supplement in Q3 FY2026 to remove the second-line indication, and management acknowledged that erosion of second-line sales may accelerate.

How does the acquisition of Actio Biosciences affect the financial position?

On August 12, 2026, Jazz announced an upfront payment of $820 million to acquire Actio Biosciences and obtain ABS-1230 to strengthen its rare epilepsy portfolio. The company had generated operating cash flow of $824 million and held approximately $2.2 billion in cash during the first half of FY2026, and it had repaid its convertible notes due in 2026. Nevertheless, the reported debt burden of $4.4 billion provides a reason to monitor the transaction's return and capital allocation discipline.