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Home
Stocks
Incyte Corporation
EL7 Factor Analysis
How we score this
Overall99
Excellent — top fifth of the marketSuper StockF 6/9Better than 99% of Market stocks, per EL7's model
FactorScoreDistributionValueAvgRank
▸
Valuation
62
15.1x▲17.8xAround median
▸
Growth
85
26.9%▲7.1%Top tier
▸
Quality
95
26.8%▲4.5%Top tier
▸
Safety
96
—2.6xTop tier
▸
Capital Return
51
—2.12%Around median
▸
Momentum
91
40.9%▲2.9%Top tier
▸
Sentiment
74
14▲3Top tier
INCY

INCY Incyte Corporation

Incyte Corporation · NASDAQ
Market Closed
121.47
▼ ⁦-1.47%⁩ (-1.81)
Market Cap$24.6B
Beta0.77
52w Low52w High
81.09132.60
Last Week
⁦-5.71%⁩
Last Month
⁦+0.75%⁩
Last 3 Months
⁦+25.56%⁩
Last Year
⁦+43.18%⁩
Fair Value
Current price$121
Analyst target · 9 analysts
$130
⁦+7%⁩
See it undervalued
Range ⁦$104–$155⁩
vs
DCF (estimate)
$187
⁦+54%⁩
Sees it clearly undervalued
⁦7.9⁩% discount · ⁦1⁩% growth
Bottom lineThe two methods broadly agree — estimate range ⁦$130–$187⁩.

Estimates — analyst targets and a simplified DCF, not investment advice.

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Analyst Consensus

This section combines price targets, revision history, analyst coverage changes, and an AI summary of what changed on the Street.

Price Target· 9 analysts setting price target
$130.07
⁦+7.1%⁩
Current Price $121.47·Median $130.00
Low
$104.00
High
$155.00
Current price
$121.47
Average target
$130.07
Street summary

Slight Increase in Consensus Despite a Decline in the Number of Analysts

The consensus price target rose over the last 30 days from 127.83 to 130.07, an increase of 2.24 or 1.75%, while remaining unchanged over the last 7 days and 1 day. However, the number of analysts included fell from 11 to 9, making the improvement in consensus limited and not reflecting a broader coverage base. The current range is between 104 and 155 versus a current price of 121.47, indicating clear divergence in estimates.

As of 2026-09-11
Revisions momentum · 30d
⁦+1.8%⁩
Average rating
★ 3.46
Hold
Analyst coverage
⁦28 (-2)⁩
Buy conviction
43%
Mixed
Rating activity · 30d
0↑ · 0↓
Target dispersion
42%
Wide
Analyst ratings over time28 analysts rating
2
10
15
1
Strong BuyBuyHoldSellStrong Sell
Rating trend — last 12 months3.36 → 3.46
Recent analyst moves
  • = Reiterate2026-09-11
    Cantor Fitzgerald
    Neutral
  • = Reiterate2026-09-01
    BMO Capital
    Market Perform
  • = Reiterate2026-08-20
    Benchmark
    Buy
Premium content
Key Financials

Ten ratios that matter, each compared against its sector median and average — so you can see whether a number is rich or cheap relative to peers in the same sector.

StockSector medianSector averagetypical sector range
MetricValuePosition within sectorVerdict
  • P/E (TTM)
    15.15x
    3.94x44.30x
    Cheap
  • Forward P/E
    17.11x
    4.64x37.16x
    Cheap
  • EV / EBITDA
    11.22x
    3.77x30.13x
    Cheap
  • FCF Yield
    7.6%
    -138.2%7.8%
    Strong
  • Revenue Growth YoY
    26.9%
    -56.9%93.8%
    Above average
  • EPS Growth YoY
    87.4%
    -160.1%130.2%
    Strong
  • Gross Margin
    92.6%
    12.8%90.7%
    Exceptional
  • ROIC
    26.8%
    -155.3%16.0%
    Exceptional
  • Net Debt / EBITDA
    —
    —
  • Dividend Yield
    —
    —
  • Payout Ratio
    —
    —
  • Altman Z-Score
    —
    —
Financial Analysis
|

Stock Analysis

AI-generated
Based on 2026-07-28 data

Company Overview

Incyte Corporation is a biopharmaceutical company that generates revenue from treatments for hematologic diseases, oncology, and inflammatory dermatologic diseases. Jakafi remains the core product and the funding source for the development pipeline and new launches, while diversification drivers include Opzelura, Niktimvo, Monjuvi, and Zynyz; in Q2 FY2026, Jakafi sales were approximately $817 million, while the core business excluding Jakafi generated approximately $671 million.

Q2 FY2026 revenue reached approximately $1.67 billion, up 38% year over year, while net product sales reached $1.49 billion, up 40%. However, the results included a one-time non-cash benefit of $246 million related to a CMS settlement; excluding it, net sales grew 17%, making the underlying growth rate significantly lower than the reported figure.

The call does not include net income for Q2 FY2026, so EDGAR data for Q1 FY2026 provides the latest complete profitability reading: revenue of $1.3 billion, gross profit of $1.2 billion, net income of $303.3 million, and earnings per share of $1.47. These figures represent a gross margin of approximately 92% and a net income margin of approximately 23%, while FY2025 recorded revenue of $5.1 billion and net income of $1.3 billion.

What's Driving the Stock

  • Incyte raised its FY2026 net sales guidance to a range of $5.130–$5.260 billion and raised the Opzelura range to $1.050–$1.100 billion, with an estimated contribution of $300–$310 million from the CMS settlement and improved net pricing after discounts.
  • Jakafi generated sales of $817 million in Q2 FY2026, up 7%, with prescription demand growth of 9%. Jakafi XR recorded sales of $10 million, primarily reflecting initial inventory build, and the company is targeting annual sales of $40–$50 million and insurance coverage of 50%–70% by the end of FY2026.
  • Reported Opzelura sales reached $450 million in Q2 FY2026, comprising $204 million in product sales and a one-time non-cash benefit of $246 million. Excluding that benefit, U.S. sales increased 22% to $161 million, prescriptions rose 26%, and the treatment captured 46% of new-to-brand prescriptions for branded topical products.
  • Sales of the hematology and oncology portfolio rose 69% to $222 million in Q2 FY2026; Niktimvo generated approximately $60 million, up 67%, Monjuvi approximately $54 million, up 72%, and Zynyz approximately $50 million, equivalent to four times its previous annual level.
  • The acquisition of Vega Therapeutics added latarcibart, a Phase 3 drug candidate for the treatment of von Willebrand disease; the VIVID-3 study showed a median 81% reduction in annualized bleeding rate with once-monthly subcutaneous dosing, compared with current prophylactic treatments that are typically administered two to three times weekly.
  • Incyte is advancing three major solid-tumor programs into pivotal development: 890, 734, and 667. 734, a KRAS G12D inhibitor, is undergoing a Phase 3 study in pancreatic cancer, while the company said it had collected data from approximately 50 patients with the gem/nab and FOLFIRINOX regimens to evaluate efficacy and safety.

Buying & Selling Case

▲ Buying Case4 pts

  • +The business outside Jakafi is growing rapidly; core business sales excluding it rose 44% in Q2 FY2026 after excluding the non-recurring Opzelura benefit, supporting management's target of reaching $3–$4 billion in net sales by 2030.
  • +The commercial portfolio combines growth from Jakafi and Opzelura with accelerating momentum from Niktimvo, Monjuvi, and Zynyz, as every product delivered year-over-year growth in Q2 FY2026, gradually reducing reliance on a single growth driver.
  • +The company held $4.5 billion in cash and cash equivalents at the end of Q2 FY2026 before the Vega transaction closed, providing flexibility to fund Phase 3 studies and product launches.
  • +The development pipeline includes advanced opportunities across hematology, oncology, and dermatology, including latarcibart in Phase 3, 989 in myeloproliferative neoplasms, and 734 in pancreatic cancer, in addition to regulatory reviews for povorcitinib and Monjuvi.

▼ Selling Case6 pts

  • −

Valuation

The average analyst price target is $130.07, within a wide range of $104 to $155, with a consensus rating of “Buy.” The average target is close to the top of the 52-week range of $132.6, while the highest target exceeds that peak and the lowest target is above the range's low of $81.09; this dispersion reflects significant differences in assessments of the development pipeline's value and the sustainability of growth after excluding the non-recurring CMS benefit.

BuyAnalyst target: $130.07(+7.1%)

Figures in the text are as of 2026-08-28; the live price is shown at the top of the page.

FAQ

How dependent is Incyte on Jakafi?

Jakafi generated sales of $817 million in Q2 FY2026 out of total net product sales of $1.49 billion, or approximately 55%. Its sales rose 7%, and prescription demand increased 9% across MF, PV, and GVHD, with PV being the largest growth driver. In contrast, the core business excluding Jakafi grew 44% after excluding the non-recurring Opzelura benefit, and management is targeting $3–$4 billion by 2030.

Why did Incyte's revenue surge in Q2 FY2026?

Revenue reached $1.67 billion in Q2 FY2026, up 38%, while net product sales reached $1.49 billion, up 40%. The result included a one-time non-cash benefit of $246 million arising from a CMS settlement and the reversal of previously accrued balances related to Medicaid rebates on Opzelura. Excluding this benefit, net sales growth was 17%, so the 40% rate does not, by itself, represent a repeatable operating pace.

What are the key growth drivers for Opzelura?

Opzelura recorded reported sales of $450 million in Q2 FY2026, comprising $204 million in product sales and a $246 million non-cash benefit. Underlying U.S. sales increased 22% to $161 million, and prescriptions rose 26% compared with market growth of 21%, while the product captured 46% of new-to-brand prescriptions for branded topical products. Internationally, sales reached $43 million, up 34%, and management sees the potential for international sales to reach two to three times the level recorded in that quarter.

Earnings callEDGAR filings30-day newsInsider activity

Automated analysis for informational purposes only — not investment advice.

Despite the portfolio's expansion, Jakafi still represented approximately 55% of net product sales in Q2 FY2026, generating $817 million out of a total of $1.49 billion; therefore, the company's transition through the expiration of its commercial protection remains dependent on the success of launches and the development pipeline.
  • −A significant portion of the Q2 FY2026 surge depended on a non-recurring item: the $246 million non-cash CMS benefit increased Opzelura sales and the total, while underlying net sales growth was 17% rather than 40% after excluding it.
  • −The Vega transaction raised FY2026 GAAP research and development and selling, general, and administrative expense guidance to $4.915–$4.995 billion, including approximately $1.270 billion for the upfront payment and transaction costs and approximately $50 million for latarcibart development; this pressures profitability before Phase 3 success is demonstrated.
  • −The development pipeline carries tangible clinical and regulatory risks; Incyte discontinued development of 058 because the data did not demonstrate a differentiated therapeutic profile, while the company is still discussing the design and endpoints of the 989 study in myelofibrosis with the FDA.
  • −734 faces direct competition in the KRAS G12D class; according to management, only two companies are conducting Phase 3 studies for first-line targeted treatment of pancreatic cancer, and it described Incyte's position as roughly aligned with competitors rather than definitively ahead of them.
  • −Insiders recorded net sales of $13.3 million through 12 sales and no purchases during the three months ending with the latest transaction on August 19, 2026. This is a weak trading signal relative to operational risks because insider sales may be prearranged unless the context proves otherwise.
  • How important is the Vega Therapeutics transaction to Incyte?

    The acquisition of Vega Therapeutics added latarcibart, a protein S modulator undergoing Phase 3 development for the treatment of von Willebrand disease. The VIVID-3 study showed a median 81% reduction in annualized bleeding rate, with once-monthly subcutaneous dosing instead of prophylactic treatments typically administered two to three times weekly. However, the transaction added approximately $1.270 billion in upfront payment and transaction costs to expense guidance, along with approximately $50 million for ongoing development in FY2026, and the company is targeting the release of initial VIVID-6 data by early 2029.

    What are the main opportunities and risks in Incyte's cancer drug pipeline?

    The company is developing 734, a KRAS G12D inhibitor, in a Phase 3 study for pancreatic cancer and is also testing it in colorectal cancer with EGFR inhibitors. The portfolio also includes 890, a bispecific antibody targeting TGF-beta receptor 2 and PD-1, and 667, a CDK2 inhibitor, both in pivotal development. Risks include direct competition within KRAS G12D and the fact that early-stage data do not guarantee success in pivotal studies or regulatory approval, as illustrated by the decision to discontinue development of 058 after it failed to achieve a differentiated therapeutic profile.