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Stocks
BillionToOne, Inc.
BLLN

BLLN BillionToOne, Inc.

BillionToOne, Inc. · NASDAQ
Market Closed
98.77
▲ ⁦+0.26%⁩ (+0.26)
Market Cap$4.5B
Beta0.34
52w Low52w High
61.96150.44
Last Week
⁦+2.72%⁩
Last Month
⁦+7.77%⁩
Last 3 Months
⁦+0.99%⁩
Last Year
—
EL7 Factor Analysis
How we score this
Overall84
Excellent — top fifth of the marketHigh FlyerF 7/8Better than 84% of Market stocks, per EL7's model
FactorScoreDistributionValueAvgRank
▸
Valuation
8
139.8x▼17.8xBottom tier
▸
Growth
96
90.1%▲7.1%Top tier
▸
Quality
72
—4.5%Top tier
▸
Safety
85
—2.6xTop tier
▸
Capital Return
72
—2.12%Top tier
▸
Momentum
71
—2.9%Top tier
▸
Sentiment
34
5▲3Bottom tier
Fair Value
Low confidenceCurrent price$99
Analyst target · 2 analysts
$125
⁦+27%⁩
See it clearly undervalued
Range ⁦$120–$130⁩
vs
DCF (estimate)
$37
⁦-63%⁩
Sees it clearly overvalued
⁦7.9⁩% discount · ⁦10⁩% growth
Bottom lineThe two methods disagree — estimate range ⁦$37–$125⁩.

Estimates — analyst targets and a simplified DCF, not investment advice.

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Analyst Consensus

This section combines price targets, revision history, analyst coverage changes, and an AI summary of what changed on the Street.

Price Target· 2 analysts setting price target
$125.00
⁦+26.6%⁩
Current Price $98.77·Median $125.00
Low
$120.00
High
$130.00
Current price
$98.77
Average target
$125.00
Street summary

BillionToOne Bullish Outlook Remains Stable

Bullish tilt

BillionToOne stock shows notable stability in analyst sentiment, with the average price target remaining constant at $127.5 over the past 30 days, indicating a potential growth gap exceeding 36% from the current price of $93.33. The forecast range is tightly clustered between $125 and $130, reflecting a consensus among covering analysts on the stock's fair value at the current stage, despite the limited number of reviewers.

As of 2026-08-16
Revisions momentum · 30d
⁦-2.0%⁩
Average rating
★ 4.00
Buy
Analyst coverage
8
Buy conviction
75%
High
Target dispersion
10%
Analyst ratings over time8 analysts rating
2
4
2
Strong BuyBuyHoldSellStrong Sell
Rating trend — last 12 months4.00 → 4.00
Recent analyst moves
  • = Reiterate2026-06-29
    Guggenheim
    Buy
  • = Reiterate2026-05-13
    Guggenheim
    Buy
  • = Reiterate2026-05-07
    BTIG
    —· $130.00
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Key Financials

Ten ratios that matter, each compared against its sector median and average — so you can see whether a number is rich or cheap relative to peers in the same sector.

StockSector medianSector averagetypical sector range
MetricValuePosition within sectorVerdict
  • P/E (TTM)
    139.82x
    3.94x44.30x
    Very expensive
  • Forward P/E
    95.44x
    4.64x37.16x
    Very expensive
  • EV / EBITDA
    90.29x
    3.77x30.13x
    Very expensive
  • FCF Yield
    0.8%
    -138.2%7.8%
    Strong
  • Revenue Growth YoY
    90.1%
    -56.9%93.8%
    Strong
  • EPS Growth YoY
    133.2%
    -160.1%130.2%
    Exceptional
  • Gross Margin
    71.3%
    12.8%90.7%
    Strong
  • ROIC
    —
    —
  • Net Debt / EBITDA
    —
    —
  • Dividend Yield
    —
    —
  • Payout Ratio
    —
    —
  • Altman Z-Score
    —
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Financial Analysis
|

Stock Analysis

AI-generated
Based on 2026-08-05 data

Company Overview

BillionToOne is a molecular diagnostics company that uses QCT technology to count molecules through genetic sequencing and sells tests in two main areas: prenatal testing under the UNITY brand and oncology testing under the NorthStar brand. Most of its revenue comes from prenatal testing, while oncology represents a smaller but faster-growing business; in Q2 fiscal 2026, prenatal revenue was $95.8 million, compared with $13.7 million for oncology, representing approximately 88% and 12% of total revenue, respectively.

In Q2 fiscal 2026, BillionToOne generated revenue of $109 million, up 64% year over year, with test volume growing 35% to approximately 196 thousand tests and the average price per test rising 21% to $551. Gross profit was $77.1 million, and gross margin increased to 70.5% from 65.3% in Q2 fiscal 2025, while the company reported operating income of $5.5 million and an operating margin of 5%.

Net income available to common shareholders was $8.1 million, or $0.15 per diluted share, compared with a net loss of $0.2 million in Q2 fiscal 2025. The company also generated $9.1 million in operating cash flow and $5.1 million in free cash flow, and ended the quarter with $549 million in cash and cash equivalents, despite operating expenses rising 59% to $71.6 million due to increased commercial and research spending.

What's Driving the Stock

  • The company increased Q2 fiscal 2026 revenue by 64% to $109 million, driven by a 35% increase in test volume and a 21% rise in average price, while the core prenatal business grew 56% to $95.8 million.
  • Oncology revenue jumped 176% to $13.7 million in Q2 fiscal 2026, and management said its sequential growth came from higher test volumes because average oncology prices remained stable; the business now represents an annualized revenue run rate of approximately $55 million.
Earnings callEDGAR filings30-day newsInsider activity

Automated analysis for informational purposes only — not investment advice.

  • UnityConfirm, launched on May 28, 2026, was ordered for more than 50% of eligible UNITY patients with high-risk pregnancy results, while the company set August 17, 2026, for expanding UNITY Fetal Antigen Screen to 130 genes with the aim of supporting penetration into health systems that prefer large panels.
  • On June 24, 2026, the company published a peer-reviewed study of NorthStar Response that included 142 patients, more than 570 samples, and 12 tumor types; it is using these data to support a MolDX Medicare coverage application, an important catalyst because Response represents approximately two-thirds of oncology test volumes.
  • BillionToOne set September 1, 2026, for expanding NorthStar Select to 102 genes and adding NorthStar Origin, which recorded 91% accuracy within the top three probabilities and 86% for the top probability in identifying tissue of origin. The company also maintained its fiscal 2026 revenue guidance of $450 million to $465 million, equivalent to annual growth of between 48% and 52%.
  • Buying & Selling Case

    ▲ Buying Case4 pts

    • +BillionToOne combines 64% revenue growth, a 70.5% gross margin, and positive operating profitability in Q2 fiscal 2026, indicating that expansion in test volumes and pricing did not come at the expense of overall profitability.
    • +The oncology business provides a second growth engine alongside UNITY; its revenue grew 176%, while MolDX coverage for NorthStar Response and the launch of the sensitive, tumor-naive MRD test could support expanded adoption, according to the fiscal 2026 timeline presented by management.
    • +Epic Aura integration could support penetration into health systems, as the company completed its first integration with a health system within two weeks and estimated that each activated health system could generate between one thousand and three thousand tests per quarter.
    • +Cash and cash equivalents of $549 million and positive free cash flow of $5.1 million in Q2 fiscal 2026 give the company the capacity to fund research, commercial expansion, and the new oncology laboratory while continuing to target profitability and positive cash flow.

    ▼ Selling Case6 pts

    • −The revenue mix depends heavily on prenatal testing, which generated $95.8 million of the $109 million in Q2 fiscal 2026; therefore, any slowdown in UNITY or change in pregnancy and testing volumes could affect the largest part of the company's business.
    • −BillionToOne operates in a competitive market that includes other prenatal and oncology testing laboratories, and its plan to gain market share depends on the differentiation of UnityConfirm, the 130-gene panel, and NorthStar Origin; if these products do not persuade physicians and health systems to switch, the expected increase in volumes may not materialize.
    • −Operating margin declined from 16% in Q1 fiscal 2026 to 5% in Q2 fiscal 2026, while operating expenses rose 59% and investment in sales and research and development increased. Management also warned that oncology growth exceeding the plan could temporarily reduce gross margin below 70% because of the lower margins of new products in their early stages.
    • −The company mutually agreed to pause the submission of more than $10 million in claims while awaiting implementation of its codes within a national payer network, temporarily affecting collections, average price, and settlements. Management does not yet know the full timing or final amount that will be collected, and fiscal 2026 revenue guidance does not include future unrecorded settlements.
    • −Converting health systems to Epic Aura requires each integration to be placed on technology roadmaps that typically span between two and four quarters, despite BillionToOne's speed of implementation after receiving approval. The company also added approximately 70 sales representatives in the first half of fiscal 2026 and acknowledged that the acceleration in hiring temporarily pressured sales productivity before their training was completed.
    • −Net insider selling totaled $22.3 million during the three months ending with the latest transaction on August 25, 2026, with 93 sales and no purchases recorded. This is a weak trading signal on its own because insider sales may be prearranged, and the provided data do not clarify the nature of these plans.

    Valuation

    The average analyst price target is $127.5, within a narrow range of $125 to $130, against a consensus rating of “Buy”; the average target is approximately 15% below the 52-week range high of $150.44. The 52-week range extends from $61.96 to $150.44, and no price-to-earnings ratio is available in the data, limiting the ability to value the stock on an earnings basis despite the company's transition to net profitability. The positive consensus should be weighed against the risks of declining operating margin, uncertainty regarding the more than $10 million in claims, and the execution required to convert Epic Aura integrations into actual volumes.

    BuyAnalyst target: $127.5(+29.1%)

    Figures in the text are as of 2026-08-31; the live price is shown at the top of the page.

    FAQ

    How did BillionToOne achieve 64% revenue growth in Q2 fiscal 2026?

    Revenue increased to $109 million from $66.6 million in Q2 fiscal 2025. Test volume grew 35% to approximately 196 thousand tests, and the average price rose 21% to $551. Prenatal revenue also increased 56% to $95.8 million, while oncology revenue jumped 176% to $13.7 million.

    What is the importance of UnityConfirm to BLLN's business?

    BillionToOne launched the UnityConfirm test on May 28, 2026, as a noninvasive confirmatory test for high-risk cases identified by UNITY aneuploidy. By the August 5, 2026, call, healthcare providers were ordering it for more than 50% of eligible patients. Management believes the product helps open doors to health systems and reduce the division of testing volumes among multiple laboratories, but described it as a long-term driver because converting health systems requires additional integrations and workflows.

    Why is the oncology business important to BillionToOne's growth?

    Oncology revenue reached $13.7 million in Q2 fiscal 2026, up 176% year over year, with an annualized run rate of approximately $55 million. Management said sequential growth came almost entirely from higher test volumes because average oncology prices did not change materially. NorthStar Response also represents approximately two-thirds of oncology test volumes, making MolDX Medicare coverage an important factor in the economics of this business.

    Can BillionToOne maintain a gross margin above 70% as oncology grows?

    Gross margin was 70.5% in Q2 fiscal 2026, compared with 65.3% in Q2 fiscal 2025. Management said the underlying margin, excluding settlements, remained close to 70% over the previous four quarters despite the mix shifting toward the less mature oncology business. However, it explained that oncology growth exceeding the plan or the launch of initially low-margin products could temporarily push the margin below 70%.

    What is BillionToOne's fiscal 2026 revenue guidance?

    The company reiterated its fiscal 2026 revenue range of $450 million to $465 million, representing growth of approximately 48% to 52% compared with fiscal 2025. This guidance does not include future settlements beyond those already recorded, and management did not assume full collection of the more than $10 million in held claims. Management expected to maintain profitability near current levels while continuing substantial commercial and research investments.

    How could Epic Aura affect BillionToOne's test volumes?

    BillionToOne completed its integration with the Epic Aura platform in less than five months and completed the first connection with a health system within two weeks from the start to the first test order. Each activated health system could generate between one thousand and three thousand tests per quarter, according to management's estimate. However, placing the integration on each health system's technology roadmap may take between two and four quarters, so the actual impact depends on how many systems prioritize the project.