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Stocks
Biogen Inc.
EL7 Factor Analysis
How we score this
Overall65
Strong — clearly above market medianHigh FlyerF 6/9Better than 65% of Market stocks, per EL7's model
FactorScoreDistributionValueAvgRank
▸
Valuation
45
38.4x▼17.8xAround median
▸
Growth
30
0.3%▼7.1%Bottom tier
▸
Quality
75
4.3%▼4.5%Top tier
▸
Safety
62
4.1x▼2.6xAround median
▸
Capital Return
21
—2.12%Bottom tier
▸
Momentum
86
42.0%▲2.9%Top tier
▸
Sentiment
63
28▲3Around median
BIIB

BIIB Biogen Inc.

Biogen Inc. · NASDAQ
Market Closed
217.15
▲ ⁦+0.80%⁩ (+1.72)
Market Cap$32.1B
Beta0.17
52w Low52w High
135.39225.80
Last Week
⁦-3.28%⁩
Last Month
⁦+3.96%⁩
Last 3 Months
⁦+8.60%⁩
Last Year
⁦+52.27%⁩
Fair Value
Current price$217
Analyst target · 9 analysts
$247
⁦+14%⁩
See it undervalued
Range ⁦$175–$300⁩
vs
DCF (estimate)
$251
⁦+16%⁩
Sees it undervalued
⁦7.9⁩% discount · ⁦0⁩% growth
Bottom lineThe two methods broadly agree — estimate range ⁦$247–$251⁩.

Estimates — analyst targets and a simplified DCF, not investment advice.

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Analyst Consensus

This section combines price targets, revision history, analyst coverage changes, and an AI summary of what changed on the Street.

Price Target· 9 analysts setting price target
$245.88
⁦+13.2%⁩
Current Price $217.15·Median $246.50
Low
$175.00
High
$300.00
Current price
$217.15
Average target
$245.88
Street summary

Target Price Consensus Rises While Dispersion Remains High

Biogen’s target price consensus rose to 245.88 from 234.60 over the last 30 days, an increase of 11.28 or 4.81%, while the increase over the last 7 days was limited to 0.95 or 0.39%. The number of analysts remained unchanged at 9, and there was no adjustment on the last day. The median target price of 246.50 is close to the consensus, but the range between 175 and 300 reflects clear divergence in estimates compared with the current price of 217.15.

As of 2026-09-11
Revisions momentum · 30d
⁦+4.8%⁩
Average rating
★ 3.71
Buy
Analyst coverage
35
Buy conviction
66%
High
Rating activity · 30d
0↑ · 0↓
Target dispersion
58%
Wide
Analyst ratings over time35 analysts rating
3
20
11
1
Strong BuyBuyHoldSellStrong Sell
Rating trend — last 12 months3.54 → 3.71
Recent analyst moves
  • = Reiterate2026-09-10
    HSBC
    Reduce
  • = Reiterate2026-09-03
    Piper Sandler
    Overweight
  • = Reiterate2026-08-25
    RBC Capital
    Outperform
Premium content
Key Financials

Ten ratios that matter, each compared against its sector median and average — so you can see whether a number is rich or cheap relative to peers in the same sector.

StockSector medianSector averagetypical sector range
MetricValuePosition within sectorVerdict
  • P/E (TTM)
    38.43x
    3.94x44.30x
    Near median
  • Forward P/E
    13.75x
    4.64x37.16x
    Cheap
  • EV / EBITDA
    22.46x
    3.77x30.13x
    Near median
  • FCF Yield
    8.4%
    -138.2%7.8%
    Exceptional
  • Revenue Growth YoY
    0.3%
    -56.9%93.8%
    Near median
  • EPS Growth YoY
    -46.0%
    -160.1%130.2%
    Near median
  • Gross Margin
    70.0%
    12.8%90.7%
    Strong
  • ROIC
    4.3%
    -155.3%16.0%
    Strong
  • Net Debt / EBITDA
    4.08x
    0.60x5.10x
    Near median
  • Dividend Yield
    —
    —
  • Payout Ratio
    —
    —
  • Altman Z-Score
    —
    —
Financial Analysis
|

Stock Analysis

AI-generated
Based on 2026-07-29 data

Company Overview

Biogen is a biotechnology company focused on treatments for neurological, rare, and immune diseases, generating revenue from the sale of drugs such as SPINRAZA, VUMERITY, SKYCLARYS, and ZURZUVAE, its share of LEQEMBI, and royalties and profit sharing related to anti-CD20 drugs. Its commercial portfolio expanded after completing the acquisition of Apellis on May 14, 2026, adding SYFOVRE and Empaveli to its revenue sources, while its Phase 3 programs target lupus, antibody-mediated rejection after kidney transplantation, and Dravet syndrome.

In Q2 fiscal year 2026, total revenue reached $2.7 billion, up 3% year over year, while core pharmaceutical revenue reached $1.8 billion, up 4% year over year and 12% sequentially. The growth portfolio generated more than $1 billion and grew 24% year over year, including $933 million from Biogen's standalone products and $128 million from SYFOVRE and Empaveli since the Apellis transaction closed; anti-CD20 royalty and profit-sharing revenue also reached approximately $514 million.

Non-GAAP cost of sales was 22% of revenue in Q2 fiscal year 2026 versus 21% a year earlier, implying a gross margin of approximately 78%. According to the earnings report published on July 29, 2026, adjusted earnings per share were $3.60 versus expectations of $2.94. The latest available EDGAR data show that Q1 fiscal year 2026 recorded revenue of $2.5 billion, gross profit of $1.8 billion, net income of $319.5 million, and earnings per share of $2.15.

What's Driving the Stock

  • The growth portfolio became larger than the legacy multiple sclerosis portfolio, generating more than $1 billion in Q2 fiscal year 2026 with year-over-year growth of 24%; within it, SPINRAZA recorded revenue of $402 million, with patients transitioning to the high dose faster than management expected.
  • LEQEMBI generated end-market revenue of $184 million in Q2 fiscal year 2026, up 15% year over year and 9% sequentially, while LEQEMBI IQLIK enables at-home dosing during both the initiation and continuation phases, potentially reducing the barrier of reliance on intravenous infusion centers.
  • SKYCLARYS recorded revenue of $168 million in Q2 fiscal year 2026, up 29% year over year and 11% sequentially, and became available in 36 countries, while management believes most of its growth will come from markets outside the United States.
  • The Apellis acquisition added two commercial growth drivers: SYFOVRE generated total quarterly revenue of $162 million, up 8% year over year, and Empaveli generated approximately $46 million, up 123%. Management expects combined sales of the two products to grow at a mid-to-high-teens rate through the end of 2028, alongside annual operating savings of at least $250 million by the end of 2027.
  • Biogen is awaiting results from five Phase 3 registrational studies across cutaneous and systemic lupus, antibody-mediated rejection, and Dravet syndrome. Specific catalysts include TOPAZ-1 and TOPAZ-2 results in Q4 fiscal year 2026, and data for litifilimab in cutaneous lupus and felzartamab in antibody-mediated rejection during the first half of 2027.
  • Management raised its fiscal year 2026 revenue guidance from a mid-single-digit decline to mid-single-digit growth and set an adjusted diluted earnings-per-share range of $12 to $13. An update published on August 22, 2026, also reported an increase in non-GAAP earnings-per-share expectations, supported by new product launches and clinical-trial catalysts.

Buying & Selling Case

▲ Buying Case4 pts

  • +The portfolio transformation demonstrated measurable progress in Q2 fiscal year 2026, as growth products surpassed the legacy multiple sclerosis portfolio and their revenue increased 24% year over year, while total revenue grew 3% despite declines in some mature drugs.
  • +Commercial growth is spread across several products rather than relying on a single asset; LEQEMBI grew 15% year over year, SKYCLARYS grew 29%, and Empaveli grew 123%, while the high-dose SPINRAZA launch supports the franchise's resilience in a highly competitive market.
  • +The Apellis transaction provides the company with immediate revenue from SYFOVRE and Empaveli, and management expects their combined sales to grow at a mid-to-high-teens rate through 2028, with the transaction becoming accretive to adjusted earnings per share in fiscal year 2027 after its dilutive impact in fiscal year 2026.
  • +The five registrational studies over the coming quarters provide substantial expansion opportunities, as management estimated the addressable market at approximately $8 billion in lupus, at least $2 billion in antibody-mediated rejection, and at least $2 billion in Dravet syndrome across Biogen's key markets.

▼ Selling Case6 pts

Valuation

The average analyst price target is $243.60, which is above the 52-week range high of $222.85, with a wide spread between the lowest target of $157 and the highest target of $300 and a consensus rating of “Buy.” This disparity reflects differing estimates regarding the ability of the growth products and the Apellis transaction to offset declines in legacy drugs, in addition to the risks of Phase 3 results and higher debt and expenses; a price-to-earnings ratio of 22.1 times was also reported in the July 29, 2026 earnings report, while the accompanying fundamental data do not provide a confirmed current multiple.

BuyAnalyst target: $243.6(+12.2%)

Figures in the text are as of 2026-08-28; the live price is shown at the top of the page.

FAQ

What drove Biogen's growth in Q2 fiscal year 2026?

Total revenue increased 3% year over year to $2.7 billion, while core pharmaceutical revenue rose 4% to $1.8 billion. The growth portfolio generated more than $1 billion, up 24% year over year and 25% sequentially, and became larger than the legacy multiple sclerosis portfolio. Performance was led by SPINRAZA, with revenue of $402 million, and SKYCLARYS, with $168 million, in addition to contributions from SYFOVRE and Empaveli after the Apellis transaction was completed on May 14, 2026.

How important is LEQEMBI IQLIK to Biogen's growth?

LEQEMBI generated end-market revenue of $184 million in Q2 fiscal year 2026, up 15% year over year and 9% sequentially. LEQEMBI IQLIK enables treatment to be administered at home during both the initiation and continuation phases, unlike the intravenous infusion protocol administered every two weeks. Management believes this option could expand patient eligibility for treatment and reduce discontinuation associated with traveling to infusion centers, while insurance access and updates to hospital protocols remain important factors for adoption.

How does the Apellis transaction change Biogen's financial profile?

The transaction added SYFOVRE and Empaveli, which together contributed approximately $128 million to Biogen's revenue from May 14 through the end of Q2 fiscal year 2026. Management expects their combined sales to grow at a mid-to-high-teens rate through the end of 2028 and to generate annual operating savings of at least $250 million by the end of 2027. In contrast, net debt reached $6.8 billion, and the company expects a $0.85 dilutive impact on adjusted earnings per share in fiscal year 2026 before the transaction becomes accretive in fiscal year 2027.

Earnings callEDGAR filings30-day newsInsider activity

Automated analysis for informational purposes only — not investment advice.

  • −The legacy drug portfolio remains under competitive and commercial pressure; VUMERITY revenue fell 7% year over year to $197 million in Q2 fiscal year 2026, while TYSABRI revenue declined 1% to $451 million amid the launch of biosimilars in the United States and Europe.
  • −A significant portion of the future growth story depends on uncertain clinical outcomes; the TOPAZ lupus programs face challenges from patient heterogeneity and a high placebo response, while felzartamab must replicate in Phase 3 the 80% resolution rate for antibody-mediated rejection observed in a small, open-label Phase 2 study.
  • −Management temporarily paused the decision to advance the BIIB091 program after proof of concept in relapsing multiple sclerosis because of market crowding and competitive developments in the BTK inhibitor class, and it has not decided on the next therapeutic indication or whether to continue development.
  • −The Apellis transaction raised net debt to $6.8 billion at the end of Q2 fiscal year 2026 and added between $120 million and $130 million to interest expense and foregone interest income in each of 2026 and 2027. The company expects the transaction to reduce adjusted earnings per share in fiscal year 2026 by approximately $0.85 before becoming accretive in fiscal year 2027.
  • −Adjusted cost of sales increased to 22% of revenue versus 21% a year earlier, and core research and development and selling and administrative expenses rose 20% year over year, including approximately $95 million of Apellis expenses after May 14, 2026. Fiscal year 2026 guidance also includes an impact of approximately $3 per share from acquired research and development expenses and milestone payments.
  • −Net insider activity during the three months ending with the latest transaction on August 4, 2026, was negative 239,749.9 across two sales and no purchases. This is a weak trading signal on its own because insider sales may be prearranged, and the available information does not identify the motivations behind the two transactions.
What are the most important trial results that could affect BIIB?

Biogen is awaiting five Phase 3 registrational results across four therapeutic indications. The announced timelines include TOPAZ-1 and TOPAZ-2 results for litifilimab in systemic lupus during Q4 fiscal year 2026, and results in cutaneous lupus and antibody-mediated rejection in the first half of 2027. The program also includes a Dravet syndrome study in partnership with Stoke, while management estimated the addressable markets at approximately $8 billion for lupus and at least $2 billion each for antibody-mediated rejection and Dravet within the markets it presented.

Does the decline in legacy multiple sclerosis drugs remain a problem?

Yes, although the growth portfolio became larger than the legacy multiple sclerosis portfolio in Q2 fiscal year 2026. VUMERITY revenue fell 7% year over year to $197 million, partly because of inventory factors, while TYSABRI revenue declined 1% to $451 million amid the launch of biosimilars in the United States and Europe. Biogen's ability to overcome this pressure depends on continued growth from LEQEMBI, SKYCLARYS, high-dose SPINRAZA, and the Apellis products.

What is Biogen's guidance for fiscal year 2026?

Management raised revenue guidance from a mid-single-digit decline to mid-single-digit growth. It set a non-GAAP diluted earnings-per-share range of $12 to $13 for fiscal year 2026. The guidance includes an impact of approximately $3 per share from acquired research and development expenses and milestone payments, in addition to dilution of approximately $0.85 related to financing the Apellis transaction.