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AstraZeneca exceeded second-quarter profit expectations on July 27, driven by strong demand for cancer and heart disease therapies. The company reaffirmed its 2026 financial outlook to ease investor concerns following a recent clinical trial failure. However, shares declined on August 3 amid reports of potential merger discussions with Bristol Myers Squibb. This decline could mark the stock's largest one-day percentage drop since the 2024 U.S. presidential election.