•Insmed announced positive topline results from the Phase 3b ENCORE study of ARIKAYCE in patients with MAC lung disease.
•The study met primary and all multiplicity-controlled secondary endpoints, showing statistically significant improvements in respiratory symptoms and culture conversion rates.
•Insmed plans to file a supplemental NDA with the FDA and submit data to Japan's PMDA in the second half of 2026.
•The Trump administration is building a portfolio of strategic assets including the Panama Canal, Venezuelan oil flows, and the Strait of Hormuz to pressure China.
•Strategist Zoltan Pozsar notes that Washington seeks to control energy chokepoints that Beijing relies on for cheap crude imports.
•Cuba is facing a severe energy crisis and power blackouts amid fears of a communist regime collapse due to US pressure.
•The European Association of Urology (EAU) upgraded Aquablation therapy to a "Strong Surgical Recommendation" for treating Benign Prostatic Hyperplasia (BPH).
•The update reflects growing clinical evidence supporting the efficacy of the robotic waterjet therapy.
•Japan's Ministry of Health, Labour and Welfare (MHLW) approved Effexor SR 37.5 mg / 75 mg capsules for the treatment of adults with generalized anxiety disorder (GAD).
•Effexor becomes the first and only approved treatment option in Japan for adults living with GAD.
•The drug is a serotonin-noradrenaline reuptake inhibitor (SNRI).
•China's National Medical Products Administration (NMPA) approved TP-03 (lotilaner ophthalmic solution) 0.25% for the treatment of Demodex blepharitis.
•The regulatory approval triggers a $15 million milestone payment due to Tarsus Pharmaceuticals.
•The drug is marketed in the United States under the brand name XDEMVY.
•Wellgistics Health (NASDAQ: WGRX) signed a non-binding Letter of Intent to acquire Neuritek Therapeutics, a neuroscience-focused research organization.
•The proposed acquisition is valued at $105 million and is intended to be an all-stock transaction.
•The acquisition aims to expand Wellgistics' healthcare platform into innovative therapies for neurological and psychiatric disorders.
•YZi Labs highlighted a systemic governance breakdown at CEA Industries and condemned a $2 million 'golden parachute' for outgoing CEO David Namdar.
•Recent filings disclosed material weaknesses in internal controls, including a lack of segregation of duties between the CEO and accounting functions.
•Potassium do Brasil, a subsidiary of Brazil Potash, formalized a Term of Commitment and Cooperation with the Mura Indigenous Council (CIM).
•The agreement aims for sustainable territorial development and improving living conditions in indigenous communities in the Autazes municipality, Amazonas.
•This step supports the Autazes Potash Project being developed by the company in the Amazon region.
•General Motors (GM) stock closed higher on Monday following management's presentation of a high-margin transformation strategy at the Bank of America Global Automotive Summit.
•Wall Street analysts expressed optimism regarding the company's profit-first roadmap.
•21Shares filed an amendment to the S-1 form for the launch of a Cronos (CRO) ETF.
•There are currently four issuers in the race for Cronos ETFs: 21Shares, Canary Capital, and two funds branded by Trump Media & Technology Group (TMTG).
•March 27 is viewed as a crucial SEC deadline that could redefine the digital asset landscape in the US.
•Katana, a DeFi blockchain incubated by Polygon Labs and GSR, has acquired the decentralized exchange IDEX.
•Katana officially launched Katana Perps, a perpetual futures platform designed to integrate spot and derivatives trading in a single on-chain environment.
•Matthew Fisher, formerly a key player in partnerships with OKX and Binance, has taken over as the new CEO to lead the expansion strategy.
•Bitcoin reached the $70,000 level following President Trump's announcement of a five-day delay on the deadline to strike Iranian energy infrastructure.
•Altcoins including Ethereum, XRP, and Dogecoin saw an unwinding of short positions as market sentiment improved.
•The meme coin market capitalization gained approximately 3% over 24 hours to reach $33.4 billion.
•Yara's Pilbara plant in Australia, producing 850,000 tonnes of ammonia annually, will shut for two months to repair damage from a power outage.
•The plant accounts for 5% of globally traded ammonia, and its shutdown coincides with supply disruptions in the Strait of Hormuz due to the Iran conflict.
•The shutdown will impact the production of technical ammonium nitrate (TAN) used in mining explosives, as well as urea fertilizer for farmers.