•Russian President Vladimir Putin described the assassination of Ayatollah Khamenei as a 'cynical murder' and a blatant violation of international law.
•The assassination occurred as part of a US-Israeli military operation named 'Operation Epic Fury'.
•The Kremlin confirmed it is in constant contact with Iranian leadership following massive bombing raids on Tehran.
•China's Foreign Ministry urged all parties to cease military operations and ensure safe navigation in the Strait of Hormuz.
•China imports about 80% of Iran's oil exports, equivalent to approximately 1.6 million barrels per day.
•Reports indicate shipping in the Strait of Hormuz is paralyzed amid threats from Iran's Revolutionary Guards and drone strikes on Gulf energy infrastructure.
•The Phase 3 CYPRESS study evaluating ampreloxetine failed to meet its primary endpoint in patients with symptomatic neurogenic orthostatic hypotension (nOH).
•The board is accelerating a strategic review and announced an organizational restructuring to reduce the cost base by approximately 60% (around $70 million).
•The company expects a cash balance of approximately $400 million by the end of Q1 2026, shifting focus to its growing COPD product, YUPELRI.
