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Sign InAs gene therapy for eye diseases gains momentum, REGENXBIO has announced a key clinical milestone. According to reports, the first patient has been dosed in the Phase IIb/III NAAVIGATE trial of surabgene lomparvovec (ABBV-RGX-314) for diabetic retinopathy using suprachoroidal delivery. The milestone triggers a $100 million payment to the company. Additionally, long-term data from diabetic retinopathy and wet AMD programs will be presented at the American Society of Retina Specialists (ASRS) 2026 meeting.
RGNX shares closed at $10.48 on June 26, within a range of $9.94 to $10.78, per market data. The drug candidate is being developed in collaboration with AbbVie, underscoring the commercial potential. The $100 million milestone bolsters REGENXBIO's balance sheet as it advances pivotal-stage trials.
Currently trading near $10.48 (close June 26), RGNX finds support around $9.94 and resistance near $10.78. Key near-term catalysts include the ASRS 2026 data presentation and any updates from the AbbVie collaboration. The milestone payment provides additional financial flexibility for ongoing clinical programs.