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Sign InAbbVie Inc. (NYSE: ABBV) reported first-quarter 2026 sales of $15.00 billion, exceeding the consensus estimate of $14.72 billion. The robust performance of Skyrizi and Rinvoq played a crucial role in offsetting the revenue decline of Humira due to biosimilar competition. Notably, global sales for Botox Therapeutic surpassed the $1 billion mark in a single quarter for the first time, highlighting the strength of the neuroscience segment. Following these results, the company raised its 2026 annual earnings guidance to a range of $14.08 to $14.28 per share. This upward revision signals long-term stability and management's confidence in the firm's strategic growth trajectory. Investors remain focused on AbbVie's ability to maintain this momentum during its ongoing portfolio rotation toward next-generation treatments.