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Sign InAB Science SA has published new clinical data demonstrating significant long-term survival benefits for ALS patients treated with its drug candidate, masitinib. The findings, released on the medRxiv platform, show a 5-year survival rate of 42.3%, representing a twofold improvement over historical benchmarks. Notably, 49% of long-term survivors maintained a satisfactory quality of life without requiring mechanical assistance. The median overall survival reached 121 months for masitinib-treated patients, far exceeding the 42 months predicted by the ENCALS model. This positive clinical validation from the phase 2b/3 AB10015 study serves as a major catalyst for the company's valuation. Investors are closely monitoring these developments as the firm moves toward future regulatory milestones in the biotechnology sector.