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Sign InPulse Biosciences (PLSE) has officially commenced patient enrollment in its pivotal NANOPULSE-AF clinical trial. The study is designed to evaluate the safety and efficacy of the company's proprietary Nano-Pulse Stimulation (NPS) technology. This innovative treatment targets atrial fibrillation (AF), a significant and growing market within the cardiac care sector. This milestone represents a critical step for the company as it seeks regulatory approval and prepares for potential commercialization. Successfully advancing this trial is seen as a major move toward entering the large-scale cardiac treatment market. Investors view the initiation of this pivotal study as a positive indicator of the company's clinical pipeline progression.