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StocksMedium•31 March 2026•

1 min read

ORIC Pharmaceuticals Selects Phase 3 Dose for Prostate Cancer Treatment

Key Facts

1ORIC Pharmaceuticals selected 400 mg once daily as the Recommended Phase 3 Dose (RP3D) for Rinzimetostat.

2The drug will be used in combination with darolutamide for the Himalayas-1 global Phase 3 registrational trial.

Version History

1 additional source confirmed this story

ORIC Pharmaceuticals has announced the selection of 400 mg once daily as the Recommended Phase 3 Dose (RP3D) for its drug Rinzimetostat. The drug will be utilized in combination with darolutamide for the upcoming Himalayas-1 global Phase 3 registrational trial. This study specifically targets patients with post-abiraterone metastatic castration-resistant prostate cancer (mCRPC). The clinical trial initiation is currently projected for the first half of 2026, following positive dose optimization data that supports its potential as a best-in-disease treatment. This selection marks a significant clinical milestone for the biotech company, signaling steady progress toward potential commercialization. Investors view this development as a positive step in ORIC's oncology pipeline, despite the trial start being scheduled for 2026.