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Sign InTenaya Therapeutics and Alnylam Pharmaceuticals have announced a strategic research collaboration aimed at discovering novel genetic targets for cardiovascular diseases. Under the agreement, Tenaya will receive up to $10 million in upfront payments, along with research funding and potential milestone payments totaling $1.13 billion. The partnership leverages Tenaya's specialized expertise in heart disease target validation and Alnylam's industry-leading RNAi therapeutic platform. This collaboration focuses on developing disease-modifying treatments to address the underlying causes of various heart conditions. For Tenaya, the deal provides a significant capital infusion and long-term financial upside relative to its current market valuation. Meanwhile, Alnylam expands its therapeutic reach into the high-impact cardiovascular sector through this joint effort.