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इस कंटेंट को एक्सेस करने के लिए मुफ्त साइन अप करें
मुफ्त अकाउंट बनाएंPalisade Bio (Nasdaq: PALI) announced positive topline results from its Phase 1b study of PALI-2108, an oral PDE4 inhibitor targeting Crohn's disease. The study demonstrated significant clinical activity, with the drug showing a 47.5% reduction in the SES-CD score, a key indicator of endoscopic improvement. Notably, 40% of the participating patients achieved both endoscopic response and remission within just two weeks of treatment. The trial successfully met its primary endpoints for safety and tolerability, providing a strong foundation for further clinical development. Following these favorable results, the company plans to advance PALI-2108 into Phase 2 clinical trials for patients with moderate to severe Crohn's disease. This development marks a significant milestone for the biotech firm as it seeks to address unmet needs in fibrostenotic Crohn's disease.